E-cadherin: Its dysregulation in carcinogenesis and clinical implications

SHM Wong, CM Fang, LH Chuah, CO Leong… - Critical reviews in …, 2018 - Elsevier
cellular functions in the context of carcinogenesis as well as its … ) and methionine (M92) from
the acceptor pocket of E-cadherin … Discoidin domain receptor (DDR) 1 is a receptor tyrosine …

Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting

ES Antonarakis, AJ Armstrong, SM Dehm… - Prostate cancer and …, 2016 - nature.com
… exon of AR-V7) splice acceptor. Further, knockdown of these factors impaired splicing of
exon 3 to CE3 but not exons 3 to 4 in LNCaP95, a cell line derived from the parental LNCaP line …

[HTML][HTML] Cell of origin of glioma: biological and clinical implications

SR Alcantara Llaguno, LF Parada - British journal of cancer, 2016 - nature.com
… repeat with splice acceptor) system that employs Rous sarcoma virus-based vectors that
are then injected into mice expressing the TVA receptor under the control of cell type-specific …

[PDF][PDF] Clinical implications and pathological associations of circulating mitochondrial DNA

E Tuboly, D McIlroy, G Briggs, N Lott… - Frontiers in Bioscience …, 2017 - core.ac.uk
… and Fas ligand binding to cell surface receptors (44). The activation of such receptors can
lead to a … This process is mediated through caspase-8 (anti-cell death enzyme) and receptor

Dichotomous function of IL-33 in health and disease: from biology to clinical implications

H Braun, IS Afonina, C Mueller, R Beyaert - Biochemical Pharmacology, 2018 - Elsevier
… that in mast cells the stem cell factor (SCF) receptor c-Kit … if IL-33 receptor/c-Kit cross-activation
is mast cell-specific or … Recently, a mutation affecting a canonical acceptor splice site …

[HTML][HTML] Biogenesis, functions, and clinical implications of circular RNAs in non-small cell lung cancer

Y Liu, X Ao, W Yu, Y Zhang, J Wang - Molecular Therapy-Nucleic Acids, 2022 - Elsevier
… Non-small cell lung cancer (NSCLC) is a major pathological type of LC and accounts for
more than 80% of all … Moreover, we highlight their clinical implications in NSCLC treatment. …

[HTML][HTML] Circular RNAs in osteoarthritis: indispensable regulators and novel strategies in clinical implications

W Zhang, L Qi, R Chen, J He… - Arthritis …, 2021 - arthritis-research.biomedcentral.com
… Spliceosome at the 5′ donor site attacking the 3′ acceptor … by the cell surface pattern-recognition
receptors (PRRs) can … Investigation of the OA synovium immune cell indicated that …

[图书][B] Iron metabolism: from molecular mechanisms to clinical consequences

R Crichton - 2016 - books.google.com
… The structure of the transferrin receptor and its central role in cellular iron uptake from
transferrin precedes a summary of other potential sources of cellular iron uptake, and the chapter …

Cellular effects and clinical implications of SLC2A3 copy number variation

GC Ziegler, P Almos, RV McNeill… - Journal of Cellular …, 2020 - Wiley Online Library
… In cancer cells, GLUT3 overexpression contributes to the Warburg effect by answering the
cell's increased glycolytic demands. The SLC2A3 gene locus at chromosome 12p13.31 is …

The role of non-coding RNAs in ABC transporters regulation and their clinical implications of multidrug resistance in cancer

Y Wang, Y Wang, Z Qin, S Cai, L Yu… - Expert Opinion on …, 2021 - Taylor & Francis
… obstacle toward successful cell proliferation and metastasis … , including disturbance of
diverse cell signaling involved in … receptors [5], post-translational modification as well as cell